The Dow had its worst daily performance since March as US stocks closed with massive losses Tuesday.
The blue-chip index lost almost 431 points, or 1.29%, to end the session at 33,002 as it dove into negative territory for the year.
The S and P 500 fell nearly 59 points, or 1.37%, to finish at 4,229. The Nasdaq plummeted 248 points, or 1.87%, to 13,059.
The VIX volatility index, also known as the fear index, jumped 12.4% to 19.80.
The 10-year US Treasury yield, meanwhile, increased 2.6% to 4.810% — its highest in more than 16 years.
The dollar index was up 0.1% to 107.00, while the euro fell 0.06% to $1.0470 against the greenback.
Precious metals were mixed, with gold losing 0.2% to $1,824 per ounce, but silver rising 0.76% to $21.21.
Oil prices gained around 0.6%, with global benchmark Brent crude at $91.13 per barrel and US benchmark West Texas Intermediate crude at $89.56.
Source: Anadolu Agency