918 COVID-19 cases and 24 deaths in Cyprus by May 19, fatality rate 2.6%, 20.6% of cases were health workers

As of May 19th, a total of 918 COVID-19 cases and 24 deaths (case fatality rate: 2.6%) have been reported in the Republic of Cyprus. Among these cases, 20.6% are health-care workers (n = 189) – 4.3% physicians (n = 39), 10.3% nurses (n = 95), 1.4% other health occupations (n = 13), and 4.6% auxiliary staff (n = 42).

 

The median age of cases is 45 years (interquartile range – IQR: 32-59 years); 49.8% are male and 50.2% are female.

 

The figures are included in the National Surveillance Report presented on Thursday by Assistant Professor GeorgiosNikolopoulos, during a press conference at the Health Ministry.

 

According to the figures, overall, of 773 cases for which the place of exposure was known, locally acquired infections (index cases and close-contacts of confirmed cases) were 643 (83.2%) – of these 8.9% (n = 57) were related to a health-care facility (General Hospital in Pafos) and 12.8% (n = 82) were reported in Aradippou municipality.

 

In total, 19% (n = 174) of cases received hospital care, of which 139 (79.9%) have been discharged alive from the hospital. Median age of all hospitalized patients is: 62 years (interquartile range: 49-73 years) and 64.9% are males.

 

Four patients were still in intensive care units (for part of the day if they died, were discharged or transferred on that day or for the whole day, by May 19th); three of them were intubated.

 

Overall, 561 (61.1%) cases have recovered (two negative tests following their diagnosis). A total of 90,619 tests have been performed as of May 19th (10,345.8 per 100,000 population).

 

The median time between symptoms onset and date of sampling was 4 days (Interquartile range – IQR: 2-7 days). It should be noted that for 14 cases the date of sample collection was before the onset of symptoms because of immediate testing of contacts of possible and laboratory-confirmed cases.

 

As of May 19th, the 14-day cumulative incidence rate of COVID-19 (per 100,000 population), a measure which reflects the number of active COVID-19 cases in the population (prevalence)1, is 4.2 per 100,000 population.

 

Among all cases, 356 (38.8%) were reported in Nicosia district, 239 (26%) in Larnaka, 158 (17.2%) in Pafos, 103 (11.2%) in Limassol, 41 (4.5%) in Ammochostos, and 21 (2.3%) were reported either in the British bases or had a residence abroad, or information was not available .

 

Notably, 125 cases (13.6%) were reported in Aradippou, a municipality in Larnaka district (Table A1 in appendix). Cases in Aradippou, including a cluster in a local bakery production line, are mainly males (58.4%; n = 73) and the median age is 49 years (IQR: 33-61 years). If the cluster is excluded, cases are mainly female (53.6%; n = 52) and the median age is 55 years (IQR: 39-69years).

 

Place of exposure is available for 773 cases (84.2%).

 

In total, 16.8% (n = 130) of laboratory-confirmed COVID-19-cases had history of travel or residence abroad during the 14 days prior to symptom onset (imported). These cases have a direct link to the UK and Greece, mainly.

 

Locally acquired infections (index cases and close-contacts of confirmed cases) occurred in 83.2% (n = 643 of 773 with known place of exposure) of the cases, of which 8.9% (n = 57) were related to a health-care facility (General Hospital in Pafos).

 

Of all cases in Aradippou (Larnaka district) (n = 125), 82 (65.6%) were locally-acquired, 10 (8%) imported and for 33 cases (26.4%) the epidemiological link was not recorded at the moment.

 

Of the 918 laboratory-confirmed COVID-19-cases, clinical information is available for 98.5% (n = 904), of which 31.6% (n = 286) reported no symptoms at diagnosis and 68.4% (n = 618) reported at least one symptom. The most commonly reported symptoms were:

 

  • cough (309/892; 34.6%),

 

  • fever (289/891; 32.4%),

 

  • myalgia (200/890; 22.5%),

 

  • sore throat (157/888; 17.7%),

 

  • anosmia (108/800; 13.5%), and

 

  • shortness of breath (105/875; 12%).

 

Other reported symptoms were diarrhoea, runny nose, and headache.

 

Information on comorbidities was available for 809 (88.1%) cases. Of these, 330 (40.8%) reported at least one comorbidity.

 

The most commonly reported comorbidities were:

 

  • hypertension (127/801; 15.9%),

 

  • diabetes (73/809; 9%),

 

  • heart disease (63/804; 7.8%), and

 

  • cancer (25/809; 3.1%).

 

Other reported comorbidities were chronic kidney disease, autoimmune disease, and chronic respiratory disease.

 

The figures show that 24 deaths were reported in Cyprus (Case Fatality Rate – CFR: 2.6%).

 

The mortality rate for COVID-19 is 2.7 per 100,000 population.

 

Seventeen deaths (70.8%) occurred in men and seven (29.2%) in women; the median age of all deaths was 76 years (IQR: 67-79 years). Nine deaths were reported among residents in Larnaka, seven in Pafos, three in Nicosia and Ammochostos, each, and two in Limassol .

 

The median time from date of sampling to death was 10 days (IQR: 4.5-23.5 days). For 17 deaths, COVID-19 was the underlying cause of death (COVID-19 CFR: 1.9%).

 

In total, 19% (n = 174) of people with COVID-19 received hospital care, and 139 patients (79.9%) have been discharged alive from the hospital. The median age of hospitalized patients was 62 years (IQR: 49-73 years). Hospitalized cases were mainly males (n = 113; 64.9%).

 

Overall, 32 cases (18.4% of all hospitalized patients) have been admitted to ICU4, of which 4 were still in ICU (as of May 19th).

 

A total of 27 ICU patients (84.4% of all ICU patients) have been intubated, of which 3 (75% of all patients currently in ICU) are still intubated.

 

The overall median length of stay in ICU (for all 32 ICU cases, considering those still in ICU until May 19th) was 11 days (IQR: 8-27.5 days). Figure A4 shows the Kaplan-Meier curve of the length of stay in ICU.

 

For patients who died while in ICU (n = 16), the median length of stay in ICU was 10.5 days (IQR: 5.5-23.5).

 

For patients transferred/discharged alive from ICU (n = 12), the median length of stay in ICU was 9 days (IQR: 7.5-27.5 days).

 

The median age of patients ever admitted to ICU was 65.5 years (IQR: 56-75 years). ICU patients are mainly male (n = 23; 71.9%).

 

The number of cases currently in ICU is 0.5 per 100,000 population. For comparison, Italy and Lombardia reported the highest rates of 6.7 per 100,000 population (n = 4,068) and 13.8 per 100,000 population (n = 1,381) on April 3rd . The ICU rates in Italy and Lombardia on May 19th are 1.2 per 100,000 population (n = 716) and 2.4 per 100,000 population (n = 244) .

 

As of May 19th, 61.1% (n = 561) of COVID-19 cases have recovered.

 

The median time between the second negative result and the first date of sampling was 23 days (IQR: 19-32 days).

 

For symptomatic cases, or for cases hospitalised, a COVID-19 case can be considered cured after the resolution of symptoms and two negative tests for SARS-CoV-2 at 24-hour interval at least.

 

For asymptomatic cases, or for persons isolated at home, the negative tests to document virus clearance should be obtained at a minimum of 14 days after the initial positive test (end of the quarantine period).

 

As of May 19th, in Cyprus the reporting rate was 104.8 cases per 100,000 population, the mortality rate was 2.7 deaths per 100,000 population and the CFR was 2.6%.

 

The report was produced by the Epidemiological Surveillance Unit of the Ministry of Health.

 

Contributors: Annalisa Quattrocchi, IoannisMamais, ValentinosSilvestros, Anna Demetriou (Health Monitoring Unit), Maria Athanasiadou (Health Monitoring Unit), TheopistiKyprianou (Health Monitoring Unit), AndroullaStylianou, SotiroulaSotiriou, FaniTheofhanous, Christos Charalambous, IoannaGregoriou, Maria Koliou, GeorgiosNikolopoulos and ElisavetConstantinou

 

Scientific Committee: ElisavetConstantinou, ConstantinosConstantinou, NikiPaphitou, GeorgiosNikolopoulos, Maria Koliou, George Panos, EiriniChristaki, Zoi – Dorothea Pana, ConstantinosTsioutis, LeondiosKostrikis, Peter Karayiannis, George Petrikkos, PetrosAgathangelou, George Mixides

 

Source: Cyprus News Agency

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